Using a new sterile syringe is always preferred but if you cannot, this is how to clean a syringe.
This guide has been written collaboratively by people with lived experience of substance use, nursing students, harm reductionists, and medical professionals to address medical issues that may affect people who use drugs. This is a helpful tool for people who use drugs in South Carolina or any participant of a South Carolina syringe exchange.
**different manufacturers may have different instructions
What is a Community Distributor? State statute defines a Community Distributor as “an organization, either public or private, which provides substance use disorder assistance and services, such as counseling, homeless services, advocacy, harm reduction, alcohol and drug screening, and treatment to individuals at risk of experiencing an opioid-related overdose” (S.C. Code Section 44-130-20(2)).
This law protects Community Distributors from any civil liability or criminal prosecution. S.C. Code Section 44-130-70(D) provides that “A community distributor that distributes an opioid antidote in accordance with the provisions of this section is not as a result of an act or omission subject to civil or criminal liability.”
The use of Intramuscular (IM) naloxone and syringes are legal under the South Carolina Joint Protocol. Learn more the Joint Protocol and how to administer naloxone by clicking the button below.
We are thrilled to publicly share some highlights of our work from the last 12 months.
Challenges Inc SC Public Health Flyer
Please feel free to download, print, and share this resource for general public wanting to learn more about Harm Reduction in South Carolina.
Challenges Inc SC Services Flyer
Please feel free to download, print, and share this resource for people who use drugs who want to learn more about Harm Reduction in South Carolina.
Challenges Inc SC Mail Program
Please feel free to download, print, and share this resource for those needing Harm Reduction supplies in South Carolina.

The purpose of this Impact Report is to share how Challenges Inc SC has saved lives, supported communities, and advanced harm reduction across the Upstate and beyond. By combining data with personal stories, we demonstrate our accountability to funders and partners, celebrate the dignity and resilience of our participants, and highlight the urgent need for continued support to sustain and grow this work.