Harm Reduction with Addiction Treatment- Greenville, S.C.


Greenville County-Overdose Map

About Us


Challenges INC. - Harm Reduction Services

Challenges Inc and Carolina Wellness and Recovery of Powdersville have joined forces to offer everything under one roof. We now provide harm reduction methods and medication assisted treatment together. Challenges Inc is a service using Harm Reduction in Greenville, S.C. We keep drug users safe by providing clean supplies and prevent overdose deaths by giving naloxone (Narcan). We are a "bridge" from addiction to recovery, using referrals and other resources to get people the help they need. At Challenges Inc., our mission is to reduce the damage caused by drugs on users and the community alike. All of our services are FREE and CONFIDENTIAL and require NO personal information. 

Find out more


  • buprenorphine treatment
  • naltrexone treatment
  • opioid and alcohol detox
  • advocacy
  • fentanyl test strips
  • clean supplies
  • condoms
  • naloxone-overdose prevention
  • sharps (bio-hazard) containers
  • education
  • treatment resources
  • community outreach

naloxone, Narcan, overdose, opioid

Things We Do // Things We Don't

  1. We DO NOT promote drug use
  2. We DO keep drug users safe
  3. We DO offer addiction treatment
  4. We DO prevent spread of disease
  5. We DO save tax payer money
  6. We DO save lives.

How Does It Work?

We are a non-profit organization in Greenville, S.C. and are 100% volunteer operated. We have found that participants of a program like ours are 5x more likely to enter into treatment than those who are not. These services can also decrease the spread of diseases like HIV and Hep C by up to 80%! It is for these reasons and many more that we decided to start a Harm Reduction program in Greenville, S.C.  To see some of our work, check out the "In the News" page on our website. 

We are able to do this work because of donations from community members.  To make a contribution, please visit the section below. If you would like to make a tax exempt donation, please email help@challengesinc.org for more information. Thank you for your support, and please do not hesitate to ask any questions you may have.


Help Our Cause

Your support and contributions will enable us to continue carrying out this life saving work.

Pay with PayPal or a debit/credit card



Contact Us

Drop us a line!

Recovery Institute of South Carolina 


is proud to endorse the initiative of: 

Challenges INC.

103 Clair Drive, Piedmont, South Carolina 29673, United States

(864) 214-6181 Suite C


Mobile as needed

In-office 9-5 Mon-Thurs

9-12 Fri

Or, find our

Mobile Location posted on Facebook